Bulk Tumor Sequencing
Bulk tumor DNA and RNA sequencing is done on a variety of patient-derived tumor samples to understand the basic biology of each specific cancer type and analyze mechanisms of response and resistance to treatment.
Single Cell RNA-seq
Genomic and transcriptomic studies have added immense value to the landscape of cancer biology, but it is clear that epigenetic modifications and epigenetic changes correlate with dynamic changes in tumoral behavior.
While multi-omic approaches to cancer tumor analysis have yielded insights into mechanisms of tumorigenesis, metastasis, and drug response, parallel tumor imaging yields histologic and geographic information about multiple cell types in the tumor and microenvironment.