Blood-Based Analysis
Our lab focuses on blood-based techniques for assessing changes in the tumor microenvironment through analysis of circulating exosomes.
Peripheral Blood Mononuclear Cells
We isolate peripheral blood mononuclear cells (PBMCs), which play a vital role in the immune response, from patient-derived blood samples. We process patient-derived samples immediately after they are obtained so as to preserve viable cells, which can be analyzed in the future.
Intracellular RNA
We extract intracellular RNA from patient-derived liquid biopsies. This extracted RNA is used to generate gene expression profiles of circulating tumor cells and lymphocytes.
Circulating free DNA
We utilize a technique to eliminate cells from liquid biopsies. This leaves behind circulating free DNA (cfDNA), which includes circulating tumor DNA, and can be used to assess changes in the blood.
Exosome Analysis
We isolate exosomes from liquid biopsies and analyze them for the presence of blood-based biomarkers.